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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc40a1tm1Dgen
targeted mutation 1, Deltagen
MGI:3604568
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc40a1tm1Dgen/Slc40a1tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606631
ht2
 		Slc40a1tm1Dgen/Slc40a1+ involves: 129P2/OlaHsd * C57BL/6 MGI:3606633


Genotype
MGI:3606631
hm1
Allelic
Composition		 Slc40a1tm1Dgen/Slc40a1tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc40a1tm1Dgen mutation (1 available); any Slc40a1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between somite formation and embryo turning, complete penetrance ( J:101679 )
• partially resorbed homozygous embryos are detected at E8.5 but not at later stages




Genotype
MGI:3606633
ht2
Allelic
Composition		 Slc40a1tm1Dgen/Slc40a1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc40a1tm1Dgen mutation (1 available); any Slc40a1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased thermal nociceptive threshold ( J:101679 )
• exhibit a significant decrease in thermal response latency during hot plate testing




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory