hematopoietic system
• at 49 days of age spleen size, weight, and spleen weight to body weight ratio are increased in homozygous males
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• a moderate to severe diffuse increase in extramedullary hematopoiesis is seen in homozygous males at 49 days of age
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• in homozygous males at 49 days of age hemoglobin, hematocrit, and red blood cell count are decreased
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• at 49 days of age the bone marrow myeloid:erythroid ratio is increased in homozygous males
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• mild red blood cell abnormalities including anisocytosis, poikilocytosis, and polychromasia are seen in homozygous males at 49 days of age
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• seen in homozygous males at 49 days of age
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• seen in homozygous males at 49 days of age
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• the percentage of neutrophils is mildly to moderately increased in homozygous males at 49 days of age
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immune system
• at 49 days of age spleen size, weight, and spleen weight to body weight ratio are increased in homozygous males
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• the percentage of neutrophils is mildly to moderately increased in homozygous males at 49 days of age
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growth/size/body
• at 49 days of age spleen size, weight, and spleen weight to body weight ratio are increased in homozygous males
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