All Phenotypes Ppm1f<tm1Dgen> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ppm1f^tm1Dgen
targeted mutation 1, Deltagen
MGI:3604597

Summary

2 genotypes

Allelic Composition	Ppm1f^tm1Dgen/Ppm1f^tm1Dgen
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1f^tm1Dgen mutation (1 available); any Ppm1f mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no homozygous mice identified at weaning and the genotypic ratio suggests either embryonic or perinatal lethality

Allelic Composition	Ppm1f^tm1Dgen/Ppm1f⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1f^tm1Dgen mutation (1 available); any Ppm1f mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased locomotor activity ( J:101679 )

• exhibit an increase in total distance traveled during open field testing, indicating possible hyperactivity

• significant increase in latency to lick a hindpaw or jump during hot plate testing, indicating a possible increase in pain threshold

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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