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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gria1tm2Rlh
targeted mutation 2, Richard L Huganir
MGI:3605220
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gria1tm2Rlh/Gria1tm2Rlh B6.Cg-Gria1tm2Rlh MGI:3817235
hm2
 		Gria1tm2Rlh/Gria1tm2Rlh involves: 129 * C57BL/6 MGI:3700130


Genotype
MGI:3817235
hm1
Allelic
Composition		 Gria1tm2Rlh/Gria1tm2Rlh
Genetic
Background		 B6.Cg-Gria1tm2Rlh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria1tm2Rlh mutation (1 available); any Gria1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dendrite morphology ( J:141127 )
• motor neurons exhibit a 25% reduction in branching, a reduction in average dendrite length, a shortening of the longest branch and an overall reduction in tree size compared to in wild-type mice




Genotype
MGI:3700130
hm2
Allelic
Composition		 Gria1tm2Rlh/Gria1tm2Rlh
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria1tm2Rlh mutation (1 available); any Gria1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:101578 )
N
• mice exhibit exhibit normal synaptic plasticity




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory