Analysis Tools
muscle
muscle spasm
(
J:87349
)
|
• hind legs of mutant mice exhibit intermittent spasms
|
|
• mutant mice keep their hind legs splayed
• the forelegs, as well as the hind legs, of some mice are affected, being turned inward with apparent plantar flexion
|
behavior/neurological
limb grasping
(
J:87349
)
|
• when a mutant mouse is lifted by its tail, its hind limbs are drawn toward the body
|
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• mutant mice exhibit head jerking both at rest and during movement
|
|
• mutant mice exhibit head jerking both at rest and during movement
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endocrine/exocrine glands
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• standard pathology examination of three mutant mice aged 18 - 26 days revealed hypercellular pancreatic islets of Langerhans in one animal that also exhibited hepatic wasting
|
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• standard pathology examination of three mutant mice aged 18 - 26 days revealed atrophy of the thymus of one mouse
|
liver/biliary system
|
• standard pathology examination of three mutant mice aged 18 - 26 days revealed hepatic wasting in one animal that also exhibited hypercellular pancreatic islets of Langerhans
|
immune system
|
• standard pathology examination of three mutant mice aged 18 - 26 days revealed atrophy of the thymus of one mouse
|
hematopoietic system
|
• standard pathology examination of three mutant mice aged 18 - 26 days revealed atrophy of the thymus of one mouse
|
