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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Insig1tm1.1Mbjg
targeted mutation 1.1, Joseph L Goldstein
MGI:3607577
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Insig1tm1.1Mbjg/Insig1tm1.1Mbjg
Insig2tm1Mbjg/Insig2tm1Mbjg
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N MGI:3607698
cx2
Insig1tm1.1Mbjg/Insig1tm1.1Mbjg
Insig2tm1Mbjg/Insig2+
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N MGI:3607699


Genotype
MGI:3607698
cx1
Allelic
Composition
Insig1tm1.1Mbjg/Insig1tm1.1Mbjg
Insig2tm1Mbjg/Insig2tm1Mbjg
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Insig1tm1.1Mbjg mutation (0 available); any Insig1 mutation (17 available)
Insig2tm1Mbjg mutation (1 available); any Insig2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• observe 82% of the expected double homozygotes at E18.5 and none at genotyping




Genotype
MGI:3607699
cx2
Allelic
Composition
Insig1tm1.1Mbjg/Insig1tm1.1Mbjg
Insig2tm1Mbjg/Insig2+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Insig1tm1.1Mbjg mutation (0 available); any Insig1 mutation (17 available)
Insig2tm1Mbjg mutation (1 available); any Insig2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• only 3 of 12 expected mice were observed at genotyping





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory