All Phenotypes sau MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

sau
sauron
MGI:3607721

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Foxq1^sa/Foxq1⁺ sau/sau⁺	involves: 101 * BALB/cOlaHsd * C3H * C57BL/6J * C57BR	MGI:3607722
cx2	sau/Del(13)36H Foxq1^sa/Foxq1⁺	involves: 101 * BALB/cOlaHsd * C3H * C57BL/6J * C57BR	MGI:3607793

Allelic Composition	Foxq1^sa/Foxq1⁺ sau/sau⁺
Genetic Background	involves: 101 * BALB/cOlaHsd * C3H * C57BL/6J * C57BR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxq1^sa mutation (16 available); any Foxq1 mutation (29 available)
sau mutation (2 available); any sau mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased thigmotaxis ( J:101156 )

• heterozygous mice exhibit heightened anxiety in the Open Field Activity test, entering the center of the field 29% less frequently than littermate controls

Allelic Composition	sau/Del(13)36H Foxq1^sa/Foxq1⁺
Genetic Background	involves: 101 * BALB/cOlaHsd * C3H * C57BL/6J * C57BR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(13)36H mutation (0 available); any Del(13)36H mutation (0 available)
Foxq1^sa mutation (16 available); any Foxq1 mutation (29 available)
sau mutation (2 available); any sau mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:101156 )

• hemizygous progeny are born at less than one-third the expected Mendelian frequency, most dying by 16.5 days post coitum (16.5 dpc)

nervous system

holoprosencephaly ( J:101156 )

• hemizygous embyros examined at 9.5 dpc often exhibit midline forebrain defects and other aspects of holoprocencephaly

• some hemizygotes that survive to birth exhibit holoprosencephalic phenotypes of varying severity

vision/eye

abnormal eye development ( J:101156 )

• some hemizygous embryos and liveborn pups exhibit structural eye defects

cyclopia ( J:101156 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24