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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sh3glb1tm1Hgw
targeted mutation 1, Hong-Gang Wang
MGI:3608890
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sh3glb1tm1Hgw/Sh3glb1tm1Hgw involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3609013


Genotype
MGI:3609013
hm1
Allelic
Composition		 Sh3glb1tm1Hgw/Sh3glb1tm1Hgw
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh3glb1tm1Hgw mutation (1 available); any Sh3glb1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased fibroblast apoptosis ( J:102178 )
• induction of apoptosis in MEFs in response to serum withdrawal or treatment with an inducer of mitochondrial stress (TUN) is significantly delayed




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory