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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mmp9tm1Amr
targeted mutation 1, Anne M Romanic
MGI:3609228
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mmp9tm1Amr/Mmp9tm1Amr B6.Cg-Mmp9tm1Amr MGI:3618373
ht2
 		Mmp9tm1Amr/Mmp9+ B6.Cg-Mmp9tm1Amr MGI:3618374


Genotype
MGI:3618373
hm1
Allelic
Composition		 Mmp9tm1Amr/Mmp9tm1Amr
Genetic
Background		 B6.Cg-Mmp9tm1Amr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp9tm1Amr mutation (0 available); any Mmp9 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased myocardial infarct size ( J:102541 )
• following ischemia-reperfusion myocardial infarct size is decreased by 35.4% and fewer neutrophils are found in the ischemic region compared to wild-type; however the ischemic area is similar to wild-type

homeostasis/metabolism
decreased myocardial infarct size ( J:102541 )
• following ischemia-reperfusion myocardial infarct size is decreased by 35.4% and fewer neutrophils are found in the ischemic region compared to wild-type; however the ischemic area is similar to wild-type




Genotype
MGI:3618374
ht2
Allelic
Composition		 Mmp9tm1Amr/Mmp9+
Genetic
Background		 B6.Cg-Mmp9tm1Amr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp9tm1Amr mutation (0 available); any Mmp9 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased myocardial infarct size ( J:102541 )
• following ischemia-reperfusion myocardial infarct size is decreased by 17.5% compared to wild-type; however the ischemic area is similar to wild-type

homeostasis/metabolism
decreased myocardial infarct size ( J:102541 )
• following ischemia-reperfusion myocardial infarct size is decreased by 17.5% compared to wild-type; however the ischemic area is similar to wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory