About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nt5etm1Jsc
targeted mutation 1, Jurgen Schrader
MGI:3609975
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nt5etm1Jsc/Nt5etm1Jsc involves: 129S1/Sv * 129X1/SvJ * NMRI MGI:3612992


Genotype
MGI:3612992
hm1
Allelic
Composition		 Nt5etm1Jsc/Nt5etm1Jsc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nt5etm1Jsc mutation (0 available); any Nt5e mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased coronary flow rate ( J:102299 )
• basal coronary flow measured in the isolated perfused heart was significantly lower

homeostasis/metabolism
abnormal platelet physiology ( J:102299 )
• platelet cAMP but not cGMP was significantly reduced
increased susceptibility to induced thrombosis ( J:102299 )
• time to carotid artery occlusion induced by FeCl3 was significantly reduced
decreased bleeding time ( J:102299 )
• bleeding time after tail tip resection tended to be shorter but did not reach the level of significance

hematopoietic system
abnormal platelet physiology ( J:102299 )
• platelet cAMP but not cGMP was significantly reduced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory