Analysis Tools|
Allele Symbol Allele Name Allele ID |
Adora2atm1Dyj targeted mutation 1, Yuan-Ji Day MGI:3611746 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in response to the adenosine (A2a) agonist KW-6002, locomotion is induced in male control animals but not in conditional knockout mice
• enhancement of fine movement behavior in controls is observed in response to amphetamine treatment but not in knockouts
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• daily treatment with amphetamine enhances locomotor responses in male control mice but does not affect male mutants; 1 week after cessation of treatment robust locomotor sensitization persists in controls
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• control mice exhibit greater locomotor response when treated with a Grm5 antagonist, MPEP, than forebrain-specific knockout mice
(J:102700)
• in response to the adenosine (A2a) agonist KW-6002, locomotion is induced in male control animals but not in conditional knockout mice
(J:104338)
• enhancement of fine movement behavior in male controls is observed in response to amphetamine treatment but not in knockouts
(J:104338)
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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