Analysis Tools|
Allele Symbol Allele Name Allele ID |
Adora2atm1Dyj targeted mutation 1, Yuan-Ji Day MGI:3611746 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• in response to the adenosine (A2a) agonist KW-6002, locomotion is induced in male control animals but not in conditional knockout mice
• enhancement of fine movement behavior in controls is observed in response to amphetamine treatment but not in knockouts
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• daily treatment with amphetamine enhances locomotor responses in male control mice but does not affect male mutants; 1 week after cessation of treatment robust locomotor sensitization persists in controls
|
|
• control mice exhibit greater locomotor response when treated with a Grm5 antagonist, MPEP, than forebrain-specific knockout mice
(J:102700)
• in response to the adenosine (A2a) agonist KW-6002, locomotion is induced in male control animals but not in conditional knockout mice
(J:104338)
• enhancement of fine movement behavior in male controls is observed in response to amphetamine treatment but not in knockouts
(J:104338)
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/19/2024 MGI 6.24 |
|
|
|
||
