Phenotypes associated with this allele

• Allele Symbol: Del(3Cd1d2-Cd1d1)1Sbp
• Allele Name: deletion, Chr 3, Steven P Balk 1
• Allele ID: MGI:3611776
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp	either: B6NTac.129S6-Del(3Cd1d2-Cd1d1)1Sbp or (involves: 129S6/SvEvTac * C57BL/6NTac)	MGI:3619518
hm2	Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp	involves: 129S6/SvEvTac	MGI:4355893

Genotype
MGI:3619518

hm1

• Allelic Composition: Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
• Genetic Background: either: B6NTac.129S6-Del(3Cd1d2-Cd1d1)1Sbp or (involves: 129S6/SvEvTac * C57BL/6NTac)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal immune tolerance ( J:58315 )

• lack of ability to develop anterior chamber-associated immune deviation (ACAID), an example of systemic tolerance that can be elicited by introducing antigen into an immune-privileged site

Genotype
MGI:4355893

hm2

• Allelic Composition: Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
• Genetic Background: involves: 129S6/SvEvTac

immune system

decreased NK T cell number ( J:151699 )

• Valpha14 invariant NK T cell numbers are not found in these mice

abnormal dendritic cell antigen presentation ( J:151699 )

• dendritic cells loaded with alphaGal-Cer are defective in activating wild-type Valpha14 invariant NKT cells

hematopoietic system

decreased NK T cell number ( J:151699 )

• Valpha14 invariant NK T cell numbers are not found in these mice