All Phenotypes Cdkn1b<tm2Jro> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdkn1b^tm2Jro
targeted mutation 2, James M Roberts
MGI:3611831

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdkn1b^tm2Jro/Cdkn1b^tm2Jro	involves: 129S4/SvJaeSor * C57BL/6	MGI:3613029

Allelic Composition	Cdkn1b^tm2Jro/Cdkn1b^tm2Jro
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1b^tm2Jro mutation (1 available); any Cdkn1b mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased incidence of tumors by chemical induction ( J:103819 )

• develop fewer urethane-induced lung tumors and have fewer number of large tumors, indicating decreased growth rate of tumors, than heterozygous Cdkn1b^tm1Mif mice

homeostasis/metabolism

decreased incidence of tumors by chemical induction ( J:103819 )

• develop fewer urethane-induced lung tumors and have fewer number of large tumors, indicating decreased growth rate of tumors, than heterozygous Cdkn1b^tm1Mif mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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