Phenotypes associated with this allele

• Allele Symbol: Prdx1^{Gt(OST422296)Lex}
• Allele Name: gene trap OST422296, Lexicon Genetics
• Allele ID: MGI:3611932
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdx1^Gt(OST422296)Lex/Prdx1^Gt(OST422296)Lex	B6.Cg-Prdx1^Gt(OST422296)Lex	MGI:3622751

Genotype
MGI:3622751

hm1

• Allelic Composition: Prdx1^{Gt(OST422296)Lex}/Prdx1^{Gt(OST422296)Lex}
• Genetic Background: B6.Cg-Prdx1^{Gt(OST422296)Lex}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal redox activity ( J:103909 )

• ferric-nitrilotriacetate injection (model for iron overload-induced oxidative stress) induces a greater and more prolonged increase in serum levels of aspartate aminotransferase and alanine aminotransferase compared to wild-type mice

• the half-lives of nitroxyl radicals induced by subcutaneous injection of 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl are increased compared to wild-type mice