Phenotypes associated with this allele

• Allele Symbol: Hspa1b^tm1Bwy
• Allele Name: targeted mutation 1, Byung-Woo Yoon
• Allele ID: MGI:3611984
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hspa1b^tm1Bwy/Hspa1b^tm1Bwy	B6.129P2-Hspa1b^tm1Bwy	MGI:3613141

Genotype
MGI:3613141

hm1

• Allelic Composition: Hspa1b^tm1Bwy/Hspa1b^tm1Bwy
• Genetic Background: B6.129P2-Hspa1b^tm1Bwy

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased susceptibility to ischemic brain injury ( J:103999 )

increased cerebral infarct size ( J:103999 )

• 30% greater infarction volume after induction of focal cerebral ischemia by intraluminal occlusion of the middle cerebral artery, with the infraction covering a wide area, from the basal ganglia to the cerebral cortex

homeostasis/metabolism

increased susceptibility to ischemic brain injury ( J:103999 )

increased cerebral infarct size ( J:103999 )

• 30% greater infarction volume after induction of focal cerebral ischemia by intraluminal occlusion of the middle cerebral artery, with the infraction covering a wide area, from the basal ganglia to the cerebral cortex