About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Wnt3atm1(cre)Eag
targeted mutation 1, Elizabeth A Grove
MGI:3612795
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Wnt3atm1(cre)Eag/Wnt3atm1(cre)Eag Not Specified MGI:3715645
cn2
 		Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Wnt3atm1(cre)Eag/Wnt3a+ 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ MGI:4365611
cn3
 		Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Trp73tm1(cre)Agof/Trp73+
Wnt3atm1(cre)Eag/Wnt3a+ 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ MGI:4365612
cn4
 		Itgb1tm1Mll/Itgb1tm1Mll
Wnt3atm1(cre)Eag/Wnt3a+ 		involves: 129X1/SvJ MGI:4947983


Genotype
MGI:3715645
hm1
Allelic
Composition		 Wnt3atm1(cre)Eag/Wnt3atm1(cre)Eag
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt3atm1(cre)Eag mutation (0 available); any Wnt3a mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:104373 )
N
• homozygous or heterozygous mice do not show any signs Wnt3a signaling from the hem, such as a shrunken dentate gyrus




Genotype
MGI:4365611
cn2
Allelic
Composition		 Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Wnt3atm1(cre)Eag/Wnt3a+
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Riet mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Relnrl mutation (3 available); any Reln mutation (209 available)
Wnt3atm1(cre)Eag mutation (0 available); any Wnt3a mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased Cajal-Retzius cell number ( J:153209 )
• number of Cajal-Retzius cells in the cortical marginal zone is reduced by 35% at P0




Genotype
MGI:4365612
cn3
Allelic
Composition		 Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Trp73tm1(cre)Agof/Trp73+
Wnt3atm1(cre)Eag/Wnt3a+
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Riet mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Relnrl mutation (3 available); any Reln mutation (209 available)
Trp73tm1(cre)Agof mutation (0 available); any Trp73 mutation (46 available)
Wnt3atm1(cre)Eag mutation (0 available); any Wnt3a mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased Cajal-Retzius cell number ( J:153209 )
• number of Cajal-Retzius cells (CRc) in the cortical marginal zone is reduced by 84% at P0
• nearly all CRc in the hippocampal formation are ablated




Genotype
MGI:4947983
cn4
Allelic
Composition		 Itgb1tm1Mll/Itgb1tm1Mll
Wnt3atm1(cre)Eag/Wnt3a+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm1Mll mutation (1 available); any Itgb1 mutation (60 available)
Wnt3atm1(cre)Eag mutation (0 available); any Wnt3a mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:170581 )
N
• at E15.5, mice exhibit normal Caja-Retzius localization and radial glia scaffold




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory