All Phenotypes Aco1<tm1Mwh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Aco1^tm1Mwh
targeted mutation 1, Matthias W Hentze
MGI:3613021

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aco1^tm1Mwh/Aco1^tm1Mwh	involves: 129P2/OlaHsd * C57BL/6J	MGI:3613557

Allelic Composition	Aco1^tm1Mwh/Aco1^tm1Mwh
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aco1^tm1Mwh mutation (0 available); any Aco1 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:103414 , J:104538 )

• partial penetrance of embryonic lethality, with fewer homozygotes observed at adult and perinatal stages but normal numbers at E11.5-12.5 (J:103414)

• Background Sensitivity: partial embryonic lethality is observed in a mixed 129S/C57BL/6J background and after 6 backcrosses to C57BL/6J (J:103414)

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