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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mobptm1Irg
targeted mutation 1, I R Griffiths
MGI:3613469
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mobptm1Irg/Mobptm1Irg involves: 129S1/SvImJ * C57BL/6J MGI:3613509
cx2
Mbpshi/Mbp+
Mobptm1Irg/Mobp+
involves: 129S1/SvImJ * C57BL/6J * SWV MGI:3613511


Genotype
MGI:3613509
hm1
Allelic
Composition
Mobptm1Irg/Mobptm1Irg
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mobptm1Irg mutation (0 available); any Mobp mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice have a normal phenotype
• large volumes of CNS myelin are produced by 30 days of age
• myelin is compacted and shows normal organization of the major dense line and the interperiod line
• no trend toward increased axonal diameters as has previously been reported

behavior/neurological
N
• normal motor development




Genotype
MGI:3613511
cx2
Allelic
Composition
Mbpshi/Mbp+
Mobptm1Irg/Mobp+
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J * SWV
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbpshi mutation (3 available); any Mbp mutation (32 available)
Mobptm1Irg mutation (0 available); any Mobp mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• normal with respect to axon diameter of the optic nerve





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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory