Analysis Tools
hematopoietic system
|
• exhibit a minor but significant degree of erythropenia
|
microcytosis
(
J:103414
)
|
• iron deficiency in the spleen
|
homeostasis/metabolism
|
• duodenal and hepatic iron accumulation is associated with increased ferritin L-chain expression and splenic iron deficiency is associated with decreased ferritin L-chain expression, however no differences in trans-ferrin staturation values
|
|
• iron loading of the duodenum
• however, no difference is seen in serum iron levels
|
|
• iron deficiency in the spleen
|
|
• increase in iron content in the liver
|
digestive/alimentary system
|
• iron loading of the duodenum
• however, no difference is seen in serum iron levels
|
|
• increase in iron content in the duodenum
|
immune system
|
• iron deficiency in the spleen
|
behavior/neurological
|
• locomotion is mildly affected, however do not display the neurodegenerative disorder seen in homozygous Ireb2tm1Roua mice
|
liver/biliary system
|
• increase in iron content in the liver
|
