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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Baxtm1Ofxa
targeted mutation 1, Osborne FX Almeida
MGI:3613737
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Baxtm1Ofxa/Baxtm1Ofxa involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3614346


Genotype
MGI:3614346
hm1
Allelic
Composition		 Baxtm1Ofxa/Baxtm1Ofxa
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Ofxa mutation (0 available); any Bax mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:61471 )
• in dexamethasone (DEX) treated homozygous mice, no increase in apoptosis of dentate neurons is seen whereas abundant apoptosis is seen in wild-type controls; heterozygous animals exhibit an intermediate phenotype

cellular
decreased neuron apoptosis ( J:61471 )
• in dexamethasone (DEX) treated homozygous mice, no increase in apoptosis of dentate neurons is seen whereas abundant apoptosis is seen in wild-type controls; heterozygous animals exhibit an intermediate phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory