About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Baxtm1Ofxa
targeted mutation 1, Osborne FX Almeida
MGI:3613737
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Baxtm1Ofxa/Baxtm1Ofxa involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3614346


Genotype
MGI:3614346
hm1
Allelic
Composition		 Baxtm1Ofxa/Baxtm1Ofxa
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Ofxa mutation (0 available); any Bax mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:61471 )
• in dexamethasone (DEX) treated homozygous mice, no increase in apoptosis of dentate neurons is seen whereas abundant apoptosis is seen in wild-type controls; heterozygous animals exhibit an intermediate phenotype

cellular
decreased neuron apoptosis ( J:61471 )
• in dexamethasone (DEX) treated homozygous mice, no increase in apoptosis of dentate neurons is seen whereas abundant apoptosis is seen in wild-type controls; heterozygous animals exhibit an intermediate phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory