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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Ela1-Bhlhb8)#Skz
transgene insertion #, Stephen F Konieczny
MGI:3614384
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Ela1-Bhlhb8)#Skz/? Not Specified MGI:3616714


Genotype
MGI:3616714
tg1
Allelic
Composition
Tg(Ela1-Bhlhb8)#Skz/?
Genetic
Background
Not Specified
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phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• cells expressing the transgene fail to develop into mature acinar cells and show increased expression of duct specific genes
• cells expressing the transgene are smaller and more compact with disrupted zymogen granule clustering and reduced amounts of endoplasmic reticulum
• cells not expressing the transgene develop into mature acinar cells

endocrine/exocrine glands
• cells expressing the transgene fail to develop into mature acinar cells and show increased expression of duct specific genes
• cells expressing the transgene are smaller and more compact with disrupted zymogen granule clustering and reduced amounts of endoplasmic reticulum
• cells not expressing the transgene develop into mature acinar cells





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory