All Phenotypes Ret<tm4(RET)Jmi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ret^tm4(RET)Jmi
targeted mutation 4, Jeffrey Milbrandt
MGI:3614429

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ret^tm4(RET)Jmi/Ret^tm4(RET)Jmi	involves: 129X1/SvJ * 129S1/Sv * C57BL/6	MGI:3614968

Allelic Composition	Ret^tm4(RET)Jmi/Ret^tm4(RET)Jmi
Genetic Background	involves: 129X1/SvJ * 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ret^tm4(RET)Jmi mutation (0 available); any Ret mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

hydronephrosis ( J:105047 )

• very low penetrance (1/50) of unilateral proximal ureter dilation/hydronephrosis, however these mice are viable, have normally located gonads, no overt defects in the enteric nervous system, and essentially normal kidneys

dilated ureter ( J:105047 )

• very low penetrance (1/50) of unilateral proximal ureter dilation/hydronephrosis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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