Phenotypes associated with this allele

• Allele Symbol: Ret^tm9(RET)Jmi
• Allele Name: targeted mutation 9, Jeffrey Milbrandt
• Allele ID: MGI:3614435
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ret^tm9(RET)Jmi/Ret^tm9(RET)Jmi	involves: 129X1/SvJ * 129S1/Sv * C57BL/6	MGI:3614984
ht2	Ret^tm9(RET)Jmi/Ret^tm12(RET)Jmi	involves: 129X1/SvJ * 129S1/Sv * C57BL/6	MGI:3615300

Genotype
MGI:3614984

hm1

• Allelic Composition: Ret^tm9(RET)Jmi/Ret^tm9(RET)Jmi
• Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal kidney morphology ( J:105047 )

• variable kidney abnormalities, however ureters and gonads are normal

kidney cyst ( J:105047 )

• multiple cysts in kidney rudiments

decreased renal glomerulus number ( J:105047 )

• kidney rudiments have reduced numbers of glomeruli

abnormal kidney development ( J:105047 )

• kidney development is severely affected

• kidney abnormalities include bilateral agenesis, unilateral agensis, and kidney rudiments

absent nephrogenic zone ( J:105047 )

• absence of nephrogenic zone

absent kidney ( J:105047 )

single kidney ( J:105047 )

growth/size/body

kidney cyst ( J:105047 )

• multiple cysts in kidney rudiments

Genotype
MGI:3615300

ht2

• Allelic Composition: Ret^tm9(RET)Jmi/Ret^tm12(RET)Jmi
• Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6

renal/urinary system

renal/urinary system phenotype ( J:105047 )

N • do not exhibit any major renal abnormalities