Phenotypes associated with this allele

• Allele Symbol: Cat^d
• Allele Name: d variant
• Allele ID: MGI:3615901
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cat^d/Cat^d	Not Specified	MGI:3615905

Genotype
MGI:3615905

hm1

• Allelic Composition: Cat^d/Cat^d
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal catalase activity ( J:105024 )

• low catalase activity (hypocatalasemic) in blood as compared to wildtype Cat^a mice

• catalase activity in liver, kidney and lung is lower than wild-type Cat^a mice

• catalase activity in stomach, intestine, heart and brain is higher than wild-type Cat^amice

• catalase activity in blood exhibits increased sensitivity to multiple inhibitory treatments including heat, pH, trypsin, guanidine, urea, gamma radiation, aminotriazole and formamide relative to wild-type

• catalase activity in blood exhibits decreased sensitivity to the inhibitory agents hydroxylamine and azide relative to wild-type

• catalase activity in liver and kidney exhibits increased sensitivity to the inhibitory agents guanidine, urea, and aminotriazole relative to wild-type

• catalase activity in liver and kidney exhibits decreased sensitivity to the inhibitory agent azide relative to wild-type

cellular

abnormal redox activity ( J:105024 )