All Phenotypes Del(2Hoxd8-Hoxd13)11Ddu MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Del(2Hoxd8-Hoxd13)11Ddu
deletion, Chr 2, Denis Duboule 11
MGI:3616177

Summary

13 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas	MGI:5305757
cn2	Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu Hoxa^tm1Ddu/Del(6Hoxa)1Ddu Tg(Prrx1-cre)1Cjt/0	involves: 129S2/SvPas * C57BL/6J * SJL/J	MGI:3715861
cx3	Dp(2Evx2-Atf2)59Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas	MGI:5469822
cx4	Dp(2Lnp-Atf2)60Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas	MGI:5469823
cx5	Dp(2Evx2)61Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas	MGI:5469824
cx6	Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129P2/OlaHsd * 129S2/SvPas	MGI:5469826
cx7	Dp(2Lnp)62Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S1/Sv * 129S2/SvPas	MGI:5469825
cx8	Del(2Lnp)48Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305758
cx9	Del(2)49Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305759
cx10	Del(2Evx2)51Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305760
cx11	Del(2Atf2)52Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305762
cx12	Del(2Evx2-Atf2)53Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305764
cx13	Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5305767

Allelic Composition	Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal phalanx morphology ( J:178930 )

• missing or fused phalanges at birth

fused phalanges ( J:178930 )

brachydactyly ( J:178930 )

• at birth

skeleton

abnormal phalanx morphology ( J:178930 )

• missing or fused phalanges at birth

fused phalanges ( J:178930 )

Allelic Composition	Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu Hoxa^tm1Ddu/Del(6Hoxa)1Ddu Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129S2/SvPas * C57BL/6J * SJL/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd8-Hoxd13)11Ddu mutation (0 available); any Del(2Hoxd8-Hoxd13)11Ddu mutation (0 available)
Del(6Hoxa)1Ddu mutation (0 available); any Del(6Hoxa)1Ddu mutation (0 available)
Hoxa^tm1Ddu mutation (0 available); any Hoxa mutation (0 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal forelimb zeugopod morphology ( J:114566 )

• no genuine forearm in newborn mice

absent radius ( J:114566 )

absent ulna ( J:114566 )

abnormal limb development ( J:114566 )

• abnormal segmented cartilaginous condensation is present, instead of digits, radii, or ulnae

abnormal digit development ( J:114566 )

• no genuine digits form on forelimb in newborn mice

skeleton

absent radius ( J:114566 )

absent ulna ( J:114566 )

Allelic Composition	Dp(2Evx2-Atf2)59Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:192248 )

N	• normal limb phenotype

Allelic Composition	Dp(2Lnp-Atf2)60Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:192248 )

N	• normal limb phenotype

Allelic Composition	Dp(2Evx2)61Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:192248 )

• incomplete penetrance of digit I defects

abnormal phalanx morphology ( J:192248 )

• shortened digit II with a missing phalange

brachydactyly ( J:192248 )

• shortened digit II with a missing phalange

skeleton

abnormal phalanx morphology ( J:192248 )

• shortened digit II with a missing phalange

Allelic Composition	Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129P2/OlaHsd * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal phalanx morphology ( J:192248 )

• shortened digit II with a missing phalange

brachydactyly ( J:192248 )

• shortened digit II with a missing phalange

skeleton

abnormal phalanx morphology ( J:192248 )

• shortened digit II with a missing phalange

Allelic Composition	Dp(2Lnp)62Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S1/Sv * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:192248 )

N	• normal limb phenotype

Allelic Composition	Del(2Lnp)48Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:178930 )

• shortening of digit V with missing middle phalange

abnormal phalanx morphology ( J:178930 )

• absence of the middle phalange of digit V

skeleton

abnormal phalanx morphology ( J:178930 )

• absence of the middle phalange of digit V

Allelic Composition	Del(2)49Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:178930 )

• incomplete penetrance of malformations of digit I

Allelic Composition	Del(2Evx2)51Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:178930 )

• shortening of digits II and V

Allelic Composition	Del(2Atf2)52Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:178930 )

• all digits are malformed at birth

abnormal phalanx morphology ( J:178930 )

• all digits have only 2 phalanges

skeleton

abnormal phalanx morphology ( J:178930 )

• all digits have only 2 phalanges

Allelic Composition	Del(2Evx2-Atf2)53Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal phalanx morphology ( J:178930 )

• missing or fused phalanges

fused phalanges ( J:178930 )

brachydactyly ( J:178930 )

skeleton

abnormal phalanx morphology ( J:178930 )

• missing or fused phalanges

fused phalanges ( J:178930 )

Allelic Composition	Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:178930 )

• shortening of digit II at birth, with a missing phalange

abnormal phalanx morphology ( J:178930 )

• missing phalange in digit II

skeleton

abnormal phalanx morphology ( J:178930 )

• missing phalange in digit II

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