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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(2Hoxd11-Hoxd13)16Ddu
deletion, Chr 2, Denis Duboule 16
MGI:3616203
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(2Hoxd11-Hoxd13)16Ddu/Del(2Hoxd11-Hoxd13)16Ddu involves: 129S2/SvPas MGI:3616468
cn2
 		Del(2Hoxd11-Hoxd13)16Ddu/Del(2Hoxd11-Hoxd13)16Ddu
Hoxatm1Ddu/Del(6Hoxa)1Ddu
Tg(Prrx1-cre)1Cjt/0 		involves: 129S2/SvPas * C57BL/6J * SJL/J MGI:3715863


Genotype
MGI:3616468
hm1
Allelic
Composition		 Del(2Hoxd11-Hoxd13)16Ddu/Del(2Hoxd11-Hoxd13)16Ddu
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal spinal nerve morphology ( J:103924 )
• peroneal nerve only slightly aberrant at E12.5 and E13.5, very close to normal
• locomotion and posture normal
• transformations restricted to 25th and 26th spinal roots, transforming to 24th and 25th




Genotype
MGI:3715863
cn2
Allelic
Composition		 Del(2Hoxd11-Hoxd13)16Ddu/Del(2Hoxd11-Hoxd13)16Ddu
Hoxatm1Ddu/Del(6Hoxa)1Ddu
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd11-Hoxd13)16Ddu mutation (0 available); any Del(2Hoxd11-Hoxd13)16Ddu mutation (0 available)
Del(6Hoxa)1Ddu mutation (0 available); any Del(6Hoxa)1Ddu mutation (0 available)
Hoxatm1Ddu mutation (0 available); any Hoxa mutation (0 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal forelimb zeugopod morphology ( J:114566 )
• presence of Hoxd10 leads to better-developed and ossified zeugopod
abnormal digit development ( J:114566 )
• only rod-like structures are present distally on forelimb in newborn mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory