All Phenotypes Del(2Hoxd10-Hoxd12)19Ddu MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Del(2Hoxd10-Hoxd12)19Ddu
deletion, Chr 2, Denis Duboule 19
MGI:3616539

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Del(2Hoxd10-Hoxd12)19Ddu/Del(2Hoxd10-Hoxd12)19Ddu Hoxa^tm1Ddu/Del(6Hoxa)1Ddu Tg(Prrx1-cre)1Cjt/0	involves: 129S2/SvPas * C57BL/6J * SJL/J	MGI:3715860

Allelic Composition	Del(2Hoxd10-Hoxd12)19Ddu/Del(2Hoxd10-Hoxd12)19Ddu Hoxa^tm1Ddu/Del(6Hoxa)1Ddu Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129S2/SvPas * C57BL/6J * SJL/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd10-Hoxd12)19Ddu mutation (0 available); any Del(2Hoxd10-Hoxd12)19Ddu mutation (0 available)
Del(6Hoxa)1Ddu mutation (0 available); any Del(6Hoxa)1Ddu mutation (0 available)
Hoxa^tm1Ddu mutation (0 available); any Hoxa mutation (0 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:114566 )

N	• when Hoxd13 is present, digits form on forelimb in newborn mice

abnormal forelimb zeugopod morphology ( J:114566 )

• clear forearm is observed; structure is ill-formed, reduced, and poorly ossified

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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