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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Nr5a1-cre)7Lowl
transgene insertion 7, Bradford B Lowell
MGI:3617315
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rai1tm2.1Luo/Rai1tm2.1Luo
Tg(Nr5a1-cre)7Lowl/? 		either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB) MGI:5817657
cn2
 		Rai1tm2.1Luo/Rai1+
Tg(Nr5a1-cre)7Lowl/? 		either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB) MGI:5817661
cn3
 		Leprtm1.1Chua/Leprtm1.1Chua
Tg(Nr5a1-cre)7Lowl/0 		involves: 129 * C57BL/6J * FVB MGI:3663485


Genotype
MGI:5817657
cn1
Allelic
Composition		 Rai1tm2.1Luo/Rai1tm2.1Luo
Tg(Nr5a1-cre)7Lowl/?
Genetic
Background		 either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:237687 )
N
• males exhibit no motor weakness in wire hang test

growth/size/body
increased body weight ( J:237687 )
• females are 27% heavier than controls at 20 weeks of age




Genotype
MGI:5817661
cn2
Allelic
Composition		 Rai1tm2.1Luo/Rai1+
Tg(Nr5a1-cre)7Lowl/?
Genetic
Background		 either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:237687 )
• females are 27% heavier than controls at 20 weeks of age




Genotype
MGI:3663485
cn3
Allelic
Composition		 Leprtm1.1Chua/Leprtm1.1Chua
Tg(Nr5a1-cre)7Lowl/0
Genetic
Background		 involves: 129 * C57BL/6J * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprtm1.1Chua mutation (1 available); any Lepr mutation (122 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:105327 )
• degree of obesity is about 20% of that seen in homozygous Leprtm1.2Chua mice




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory