All Phenotypes Tg(Nr5a1-cre)7Lowl MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Nr5a1-cre)7Lowl
transgene insertion 7, Bradford B Lowell
MGI:3617315

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rai1^tm2.1Luo/Rai1^tm2.1Luo Tg(Nr5a1-cre)7Lowl/?	either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)	MGI:5817657
cn2	Rai1^tm2.1Luo/Rai1⁺ Tg(Nr5a1-cre)7Lowl/?	either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)	MGI:5817661
cn3	Lepr^tm1.1Chua/Lepr^tm1.1Chua Tg(Nr5a1-cre)7Lowl/0	involves: 129 * C57BL/6J * FVB	MGI:3663485

Allelic Composition	Rai1^tm2.1Luo/Rai1^tm2.1Luo Tg(Nr5a1-cre)7Lowl/?
Genetic Background	either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1^tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:237687 )

N	• males exhibit no motor weakness in wire hang test

growth/size/body

increased body weight ( J:237687 )

• females are 27% heavier than controls at 20 weeks of age

Allelic Composition	Rai1^tm2.1Luo/Rai1⁺ Tg(Nr5a1-cre)7Lowl/?
Genetic Background	either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1^tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:237687 )

• females are 27% heavier than controls at 20 weeks of age

Allelic Composition	Lepr^tm1.1Chua/Lepr^tm1.1Chua Tg(Nr5a1-cre)7Lowl/0
Genetic Background	involves: 129 * C57BL/6J * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^tm1.1Chua mutation (1 available); any Lepr mutation (125 available)
Tg(Nr5a1-cre)7Lowl mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:105327 )

• degree of obesity is about 20% of that seen in homozygous Lepr^tm1.2Chua mice

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