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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr27tm2Msb
targeted mutation 2, Marisa S Bartolomei
MGI:3617783
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rr27tm2Msb/Rr27+
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ 		involves: 129P2/OlaHsd * C57BL/6 * DBA MGI:3620114


Genotype
MGI:3620114
cn1
Allelic
Composition		 Rr27tm2Msb/Rr27+
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr27tm2Msb mutation (1 available); any Rr27 mutation (7 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
paternal imprinting ( J:105567 )
• paternal allele specific methylation is maintained
• maternal Igf2 allele expression is detected in the neonate liver
• paternal Igf2 allele expression is reduced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory