adipose tissue
N |
• normal differentiation of adipocytes and adipogenesis
|
homeostasis/metabolism
N |
• lipolysis normal
(J:105572)
• thin layer chromatography revealed no qualitative or quantitative changes in epidermal lipids relative to control mice
(J:202513)
|
• 57% reduction in triglycerides although triglycderides are increased in the microsomal fraction of cells
|
liver/biliary system
• 57% reduction in triglycerides although triglycderides are increased in the microsomal fraction of cells
|
• on a normal diet, liver has lower lipid content
|
• on a fatty diet, density and size of lipid drops is less than in similarly fed controls although lipid levels are higher than on a normal diet
|
endocrine/exocrine glands
• the mean area of sebaceous glands is significantly reduced to approximately half the size of control glands
• however, no changes in sebaceous gland morphology or gland number are observed
|
• sebaceous glands contain significantly less cells than control glands
|
• fat content of milk is reduced about 12% from levels seen in controls
|
• sebaceous glands show a significant reduction in the number of proliferating cells relative to control glands, as determined by Ki67 staining
|
integument
• the mean area of sebaceous glands is significantly reduced to approximately half the size of control glands
• however, no changes in sebaceous gland morphology or gland number are observed
|
• sebaceous glands contain significantly less cells than control glands
|
• fat content of milk is reduced about 12% from levels seen in controls
|
• sebaceous glands show a significant reduction in the number of proliferating cells relative to control glands, as determined by Ki67 staining
|