All Phenotypes Rr27<tm3Msb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rr27^tm3Msb
targeted mutation 3, Marisa S Bartolomei
MGI:3617969

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Rr27^tm3Msb/Rr27⁺	involves: 129P2/OlaHsd * C57BL/6J	MGI:3620115

Allelic Composition	Rr27^tm3Msb/Rr27⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr27^tm3Msb mutation (0 available); any Rr27 mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal imprinting ( J:106218 )

• paternal H19 allele is expressed and Igf2 expression is reduced, particularly in the liver

• maternal Igf2 allele is expressed and H19 expression is reduced

• embryonic methylataion of the H19 prometer and 5' end is lost

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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