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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnab1tm1Mes
targeted mutation 1, Albee Messing
MGI:3619233
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcnab1tm1Mes/Kcnab1tm1Mes either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6) MGI:3619242
cx2
 		Kcnab1tm1Mes/Kcnab1tm1Mes
Kcnab2tm1Kmc/Kcnab2tm1Kmc 		involves: 129S7/SvEvBrd MGI:3619243
cx3
 		Kcnab1tm1Mes/Kcnab1+
Kcnab2tm1Kmc/Kcnab2tm1Kmc 		involves: 129S7/SvEvBrd MGI:3619244


Genotype
MGI:3619242
hm1
Allelic
Composition		 Kcnab1tm1Mes/Kcnab1tm1Mes
Genetic
Background		 either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnab1tm1Mes mutation (0 available); any Kcnab1 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:106453 )
N
• no evidence of increased mortality through 500 days of age




Genotype
MGI:3619243
cx2
Allelic
Composition		 Kcnab1tm1Mes/Kcnab1tm1Mes
Kcnab2tm1Kmc/Kcnab2tm1Kmc
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnab1tm1Mes mutation (0 available); any Kcnab1 mutation (27 available)
Kcnab2tm1Kmc mutation (1 available); any Kcnab2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:106453 )
• average life span about 114 days




Genotype
MGI:3619244
cx3
Allelic
Composition		 Kcnab1tm1Mes/Kcnab1+
Kcnab2tm1Kmc/Kcnab2tm1Kmc
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnab1tm1Mes mutation (0 available); any Kcnab1 mutation (27 available)
Kcnab2tm1Kmc mutation (1 available); any Kcnab2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:106453 )
• average life span about 133 days




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory