Phenotypes associated with this allele

• Allele Symbol: Ryr2^tm1Amks
• Allele Name: targeted mutation 1, Andrew R Marks
• Allele ID: MGI:3619529
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ryr2^tm1Amks/Ryr2^tm1Amks	involves: 129S/SvEv * C57BL/6	MGI:3619717

Genotype
MGI:3619717

hm1

• Allelic Composition: Ryr2^tm1Amks/Ryr2^tm1Amks
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal response to cardiac infarction ( J:105666 )

• homozygotes are less susceptible to myocardial infarction-induced heart failure

• in the absence of induced myocardial infarction the morphology of homozygous hearts is similar to wild-type

homeostasis/metabolism

abnormal response to cardiac infarction ( J:105666 )

• homozygotes are less susceptible to myocardial infarction-induced heart failure

• in the absence of induced myocardial infarction the morphology of homozygous hearts is similar to wild-type