Phenotypes associated with this allele

• Allele Symbol: Dpagt1^tm1Jxm
• Allele Name: targeted mutation 1, Jamey Marth
• Allele ID: MGI:3620022
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dpagt1^tm1Jxm/Dpagt1^tm1Jxm	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3620024

Genotype
MGI:3620024

hm1

• Allelic Composition: Dpagt1^tm1Jxm/Dpagt1^tm1Jxm
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:59695 )

• homozygous embryos complete preimplatation development but die between E4-5; resorbing embryos are seen through E9.5

embryo

failure of blastocyst to hatch from the zona pellucida ( J:59695 )

• cultured homozygous blastocysts do not hatch from the zona pellucida and die shortly thereafter

• chemical removal of the zona pellucida does not rescue the embryos from death; trophoblast outgrowths do not appear and embryos do not adhere to culture plates