Phenotypes associated with this allele

• Allele Symbol: Mstn^tm1.1Swel
• Allele Name: targeted mutation 1.1, Stephen Welle
• Allele ID: MGI:3620058
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mstn^tm1.1Swel/Mstn^tm1.1Swel	involves: 129S7/SvEvBrd-Hprt1 * C57BL/6J * FVB/N	MGI:3711531

Genotype
MGI:3711531

hm1

• Allelic Composition: Mstn^tm1.1Swel/Mstn^tm1.1Swel
• Genetic Background: involves: 129S7/SvEvBrd-Hprt1 * C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

increased muscle weight ( J:106054 )

• at 5 to 6 weeks, wet muscle weight is increased

• at 6 months mice have the expected double muscling

abnormal muscle physiology ( J:106054 )

• increased rate of myofibrillar protein synthesis per whole muscle

growth/size/body

decreased body weight ( J:106054 )

• some mice are very small at weaning

• however, their weights are normal at 5 to 6 weeks

increased body weight ( J:106054 )

• at 6 months mice are heavier than wild-type mice