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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fgf9tm1.1Fwan
targeted mutation 1.1, Fen Wang
MGI:3621452
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fgf9tm1.1Fwan/Fgf9tm1.1Fwan involves: 129S4/SvJaeSor * C57BL/6 MGI:3622420
cn2
 		Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9+
Shhtm1(EGFP/cre)Cjt/Shh+ 		involves: 129 * 129S4/SvJaeSor * C57BL/6J MGI:5751752
cn3
 		Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9tm1.1Fwan
Shhtm1(EGFP/cre)Cjt/Shh+ 		involves: 129 * 129S4/SvJaeSor * C57BL/6J MGI:5751753


Genotype
MGI:3622420
hm1
Allelic
Composition		 Fgf9tm1.1Fwan/Fgf9tm1.1Fwan
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf9tm1.1Fwan mutation (1 available); any Fgf9 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:106766 )
• viable and fertile with no obvious abnormalities




Genotype
MGI:5751752
cn2
Allelic
Composition		 Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9+
Shhtm1(EGFP/cre)Cjt/Shh+
Genetic
Background		 involves: 129 * 129S4/SvJaeSor * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm1Mmk mutation (0 available); any Dicer1 mutation (94 available)
Fgf9tm1.1Fwan mutation (1 available); any Fgf9 mutation (15 available)
Shhtm1(EGFP/cre)Cjt mutation (1 available); any Shh mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:224791 )
N
• mice show rescue of the lung phenotypes seen in single conditional Dicer1 mutants, showing smaller lungs, reduced epithelial dilation, mesenchymal thickness and mesenchymal proliferation




Genotype
MGI:5751753
cn3
Allelic
Composition		 Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9tm1.1Fwan
Shhtm1(EGFP/cre)Cjt/Shh+
Genetic
Background		 involves: 129 * 129S4/SvJaeSor * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm1Mmk mutation (0 available); any Dicer1 mutation (94 available)
Fgf9tm1.1Fwan mutation (1 available); any Fgf9 mutation (15 available)
Shhtm1(EGFP/cre)Cjt mutation (1 available); any Shh mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:224791 )
N
• mice show rescue of the lung phenotypes seen in single conditional Dicer1 mutants, showing smaller lungs with reduced cystic dilation of epithelial ducts




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory