All Phenotypes Lxn<tm1Yari> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lxn^tm1Yari
targeted mutation 1, Yasuyoshi Arimatsu
MGI:3622076

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lxn^tm1Yari/Lxn^tm1Yari	B6.129P2-Lxn^tm1Yari	MGI:3624980

Allelic Composition	Lxn^tm1Yari/Lxn^tm1Yari
Genetic Background	B6.129P2-Lxn^tm1Yari

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lxn^tm1Yari mutation (1 available); any Lxn mutation (8 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased thermal nociceptive threshold ( J:106948 )

• mutant mice show a significantly longer tail-flick latency when exposed to a noxious heat stimulus compared to wild-type; mutants have reduced sensitivity to acute thermal pain

• mutant mice have a longer mean jump latency compared to wild-type in the hot-plate test

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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