All Phenotypes Nod2<tm1Vmd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nod2^tm1Vmd
targeted mutation 1, Vishva M Dixit
MGI:3622092

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nod2^tm1Vmd/Nod2^tm1Vmd	B6.129-Nod2^tm1Vmd	MGI:3625287

Allelic Composition	Nod2^tm1Vmd/Nod2^tm1Vmd
Genetic Background	B6.129-Nod2^tm1Vmd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nod2^tm1Vmd mutation (0 available); any Nod2 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal cytokine secretion ( J:106976 )

• muramyl dipeptide enhances LPS-induced secretion of TNF and Il-12 p40 of macrophages from wild-type and Cias-null mice but not from Card15-null animals

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