All Phenotypes Gt(ROSA)26Sor<tm3(CAG-EGFP/Dsred2)Luo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}
targeted mutation 3, Liqun Luo
MGI:3623347

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}/Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}	involves: 129S1/Sv * 129X1/SvJ	MGI:3665429
cn2	Dscam^tm1Pfu/Dscam^tm1Pfu Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}/? Tg(Chx10-EGFP/cre,-ALPP)2Clc/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:5305036

Allelic Composition	Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}/Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo} mutation (2 available); any Gt(ROSA)26Sor mutation (994 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:113339 )

• homozygotes diaplay some lethality

reproductive system

reduced fertility ( J:113339 )

• homoygotes have low fertility; heterozygotes show no fertility defects

Allelic Composition	Dscam^tm1Pfu/Dscam^tm1Pfu Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo}/? Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dscam^tm1Pfu mutation (1 available); any Dscam mutation (106 available)
Gt(ROSA)26Sor^{tm3(CAG-EGFP/Dsred2)Luo} mutation (2 available); any Gt(ROSA)26Sor mutation (994 available)
Tg(Chx10-EGFP/cre,-ALPP)2Clc mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal amacrine cell morphology ( J:179393 )

• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

nervous system

abnormal axon fasciculation ( J:179393 )

• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

abnormal amacrine cell morphology ( J:179393 )

• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

cellular

abnormal axon fasciculation ( J:179393 )

• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

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