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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc26a6tm1Psar
targeted mutation 1, Peter S Aronson
MGI:3623454
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc26a6tm1Psar/Slc26a6tm1Psar involves: 129S6/SvEvTac MGI:3624544


Genotype
MGI:3624544
hm1
Allelic
Composition		 Slc26a6tm1Psar/Slc26a6tm1Psar
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc26a6tm1Psar mutation (1 available); any Slc26a6 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal blood homeostasis ( J:107558 )
• plasma oxalate concentration is 2.1-fold higher in mutant mice compared to wild-type
abnormal urine homeostasis ( J:107558 )
• urinary oxalate concentration is 4.1-fold higher in mutants than in wild-type
• urinary supersaturation of calcium oxalate is 62.4 in mutants compared to 16.7 in wild-type

renal/urinary system
abnormal urine homeostasis ( J:107558 )
• urinary oxalate concentration is 4.1-fold higher in mutants than in wild-type
• urinary supersaturation of calcium oxalate is 62.4 in mutants compared to 16.7 in wild-type
urolithiasis ( J:107558 )
• 88% of male and 25% of female mutants examined have visibly detectable urinary stones in their bladders at 3-6 months of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory