homeostasis/metabolism
• plasma oxalate concentration is 2.1-fold higher in mutant mice compared to wild-type
|
• urinary oxalate concentration is 4.1-fold higher in mutants than in wild-type
• urinary supersaturation of calcium oxalate is 62.4 in mutants compared to 16.7 in wild-type
|
renal/urinary system
• urinary oxalate concentration is 4.1-fold higher in mutants than in wild-type
• urinary supersaturation of calcium oxalate is 62.4 in mutants compared to 16.7 in wild-type
|
urolithiasis
(
J:107558
)
• 88% of male and 25% of female mutants examined have visibly detectable urinary stones in their bladders at 3-6 months of age
|