Phenotypes associated with this allele

• Allele Symbol: Dnah11^tm1Bknr
• Allele Name: targeted mutation 1, Martina Brueckner
• Allele ID: MGI:3623682
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnah11^tm1Bknr/Dnah11^tm1Bknr	involves: 129S1/Sv	MGI:3623762

Genotype
MGI:3623762

hm1

• Allelic Composition: Dnah11^tm1Bknr/Dnah11^tm1Bknr
• Genetic Background: involves: 129S1/Sv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal motile primary cilium physiology ( J:107740 )

• paralyzed monocilia

abnormal primitive node morphology ( J:107740 )

• at E7.5 asymmetric calcium signals are absent in 4 of 7 and bilateral in 2 of 7 homozygotes

growth/size/body

situs inversus ( J:107740 )

cardiovascular system

abnormal heart morphology ( J:107740 )

reproductive system

decreased litter size ( J:107740 )

cellular

abnormal motile primary cilium physiology ( J:107740 )

• paralyzed monocilia