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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lingo1tm1Shmi
targeted mutation 1, Sha Mi
MGI:3623893
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lingo1tm1Shmi/Lingo1tm1Shmi involves: 129S2/SvPas * C57BL/6 MGI:3624261


Genotype
MGI:3624261
hm1
Allelic
Composition		 Lingo1tm1Shmi/Lingo1tm1Shmi
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lingo1tm1Shmi mutation (0 available); any Lingo1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelination ( J:99078 )
• onset of myelination in the CNS of mutants is earlier than in wild-type; P1 spinal cords from mutants have more myelinated axon fibers than wild-type controls; oligodendrocytes cultured from mutants are more highly differentiated when cultured and more mature oligodendrocytes are observed in mutant cultures




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory