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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Palldtm1Zgwg
targeted mutation 1, Zhugang Wang
MGI:3623949
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Palldtm1Zgwg/Palldtm1Zgwg involves: C57BL/6 MGI:3624328


Genotype
MGI:3624328
hm1
Allelic
Composition
Palldtm1Zgwg/Palldtm1Zgwg
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Palldtm1Zgwg mutation (0 available); any Palld mutation (61 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygous embryos are viable until E14.5-15.5

cellular
• plated embryonic fibroblasts from mutants show a decreased ability to attach to fibronectin in a palladin dose-dependent manner
• fibroblasts from palladin-deficient mice show reduced motility compared to wild-type cells in a wound-healing assay

nervous system
• at E9.5, neural tube of mutants remains open from the midbrain to the hindbrain; mutants show herniation of the liver and intestine due to ventral closure defects

embryo
• at E9.5, neural tube of mutants remains open from the midbrain to the hindbrain; mutants show herniation of the liver and intestine due to ventral closure defects





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory