Phenotypes associated with this allele

• Allele Symbol: Aqp2^tm1.1Nlsn
• Allele Name: targeted mutation 1.1, Soren Nielsen
• Allele ID: MGI:3624697
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aqp2^tm1.1Nlsn/Aqp2^tm1.1Nlsn	involves: 129/Sv * C57BL/6	MGI:3626346

Genotype
MGI:3626346

hm1

• Allelic Composition: Aqp2^tm1.1Nlsn/Aqp2^tm1.1Nlsn
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:108291 )

• die before 2 weeks of age

renal/urinary system

kidney papillary atrophy ( J:108291 )

• papillary atrophy

hydronephrosis ( J:108291 )

• increase in pelvic space suggesting hydronephrosis

growth/size/body

postnatal growth retardation ( J:108291 )

• similar size at birth but fail to thrive