About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgb1tm2Mlkn
targeted mutation 2, Mark L Kahn
MGI:3624805
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgb1tm2Mlkn/Itgb1tm2Mlkn involves: 129/Sv * C57BL/6 * SJL MGI:3639579


Genotype
MGI:3639579
hm1
Allelic
Composition		 Itgb1tm2Mlkn/Itgb1tm2Mlkn
Genetic
Background		 involves: 129/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm2Mlkn mutation (0 available); any Itgb1 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal platelet physiology ( J:108331 )
• mildly reduced adhesion to collagen under flow is observed in an outside-in platelet activation assay

homeostasis/metabolism
abnormal platelet physiology ( J:108331 )
• mildly reduced adhesion to collagen under flow is observed in an outside-in platelet activation assay




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory