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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgb1tm2Mlkn
targeted mutation 2, Mark L Kahn
MGI:3624805
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgb1tm2Mlkn/Itgb1tm2Mlkn involves: 129/Sv * C57BL/6 * SJL MGI:3639579


Genotype
MGI:3639579
hm1
Allelic
Composition		 Itgb1tm2Mlkn/Itgb1tm2Mlkn
Genetic
Background		 involves: 129/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm2Mlkn mutation (0 available); any Itgb1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal platelet physiology ( J:108331 )
• mildly reduced adhesion to collagen under flow is observed in an outside-in platelet activation assay

homeostasis/metabolism
abnormal platelet physiology ( J:108331 )
• mildly reduced adhesion to collagen under flow is observed in an outside-in platelet activation assay




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory