growth/size/body
• weigh about 10% - 20% less than wild-type mice at 3 weeks of age
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immune system
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected
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• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
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• about a 20% reduction in cell number is seen but organ to body mass ratio is similar to wild-type
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hematopoietic system
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected
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• about a 20% reduction in cell number is seen but organ to body mass ratio is similar to wild-type
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• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
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endocrine/exocrine glands
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected
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