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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Trat1tm1Lsmn
targeted mutation 1, Luca Simeoni
MGI:3625134
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Trat1tm1Lsmn/Trat1tm1Lsmn B6.129X1-Trat1tm1Lsmn MGI:3625956


Genotype
MGI:3625956
hm1
Allelic
Composition
Trat1tm1Lsmn/Trat1tm1Lsmn
Genetic
Background
B6.129X1-Trat1tm1Lsmn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trat1tm1Lsmn mutation (0 available); any Trat1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• weigh about 10% - 20% less than wild-type mice at 3 weeks of age

immune system
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• about a 20% reduction in cell number is seen but organ to body mass ratio is similar to wild-type

hematopoietic system
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected
• about a 20% reduction in cell number is seen but organ to body mass ratio is similar to wild-type
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type

endocrine/exocrine glands
• about a 20% reduction in cell number is seen but organ to body weight ratio is similar to wild-type
• the distribution of thymic cell subpopulations is similar to wild-type and no abnormalities in T or B cell function are detected





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory