All Phenotypes Hnf4a<tm2Mwei> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hnf4a^tm2Mwei
targeted mutation 2, Mary C Weiss
MGI:3625865

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hnf4a^tm2Mwei/Hnf4a^tm2Mwei	involves: 129S2/SvPas * C57BL/6	MGI:3625882

Allelic Composition	Hnf4a^tm2Mwei/Hnf4a^tm2Mwei
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hnf4a^tm2Mwei mutation (0 available); any Hnf4a mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• insertion of the floxed neo in the alpha1 specific first intron was embryonic lethal in the homozygous mice

• homozygous embryos recovered at E10.5 was much smaller than control and rostral part of the neural tube was not closed

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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