Phenotypes associated with this allele

• Allele Symbol: Hnf4a^tm2Mwei
• Allele Name: targeted mutation 2, Mary C Weiss
• Allele ID: MGI:3625865
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hnf4a^tm2Mwei/Hnf4a^tm2Mwei	involves: 129S2/SvPas * C57BL/6	MGI:3625882

Genotype
MGI:3625882

hm1

• Allelic Composition: Hnf4a^tm2Mwei/Hnf4a^tm2Mwei
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:106993 )

• insertion of the floxed neo in the alpha1 specific first intron was embryonic lethal in the homozygous mice

• homozygous embryos recovered at E10.5 was much smaller than control and rostral part of the neural tube was not closed