immune system
• in response to inhaled LPS, mice are unresponsive without increases in Tnfa and PMNs like other BXD RI strains
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Allele Symbol Allele Name Allele ID |
Tlr4lps-2J defective lipopolysaccharide response 2 Jackson MGI:3626283 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• in response to inhaled LPS, mice are unresponsive without increases in Tnfa and PMNs like other BXD RI strains
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• in response to inhaled LPS, mice respond indistinguishably from Tlr4-deficient mice (no response)
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/22/2024 MGI 6.24 |
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