immune system
• the bone marrow contains an increase in the proportion of immature B cells and decrease in the proportion of mature B cells probably as the result of removal of cells expressing high-affinity anti-glucose-6-phosphate specificities during maturation
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• detectable levels of anti-glucose-6-phosphate IgG unlike in wild-type mice
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• 3- to 10-fold increase in the anti-glucose-6-phosphate IgM titer
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hematopoietic system
• the bone marrow contains an increase in the proportion of immature B cells and decrease in the proportion of mature B cells probably as the result of removal of cells expressing high-affinity anti-glucose-6-phosphate specificities during maturation
|
• detectable levels of anti-glucose-6-phosphate IgG unlike in wild-type mice
|
• 3- to 10-fold increase in the anti-glucose-6-phosphate IgM titer
|