Phenotypes associated with this allele

• Allele Symbol: mypy
• Allele Name: moneypenny
• Allele ID: MGI:3626351
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	mypy/mypy	C57BL/6J-mypy	MGI:3628934

Genotype
MGI:3628934

hm1

• Allelic Composition: mypy/mypy
• Genetic Background: C57BL/6J-mypy

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal macrophage physiology ( J:105543 )

• the susceptibility of activated mutant macrophages to ex vivo vesicular stomatitis virus (VSV) infection was reversed by the addition of type I interferon

increased susceptibility to Herpesvirales infection ( J:105543 )

• mice are highly sensitive to infection by mouse cytomegalovirus (MCMV)

• these mice die by day 6 following MCMV infection

increased susceptibility to Riboviria infection ( J:105543 )

• activated macrophages from these mice are susceptible to ex vivo VSV infection

hematopoietic system

abnormal macrophage physiology ( J:105543 )

• the susceptibility of activated mutant macrophages to ex vivo vesicular stomatitis virus (VSV) infection was reversed by the addition of type I interferon